JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 64 No 4 (2019): Journal of the Chilean Chemical Society
Original Research Papers

SYNTHESIS AND CHARACTERIZATION OF A CHITOSAN-BASED CITRIC ACID-CROSSLINKED ENCAPSULANT SYSTEM

Anne Bernadette s Agu
De La Salle University
Bio
Precious Japheth L Benablo
De La Salle University
Bio
Vince St D Mesias
De La Salle University
Bio
David Jr P Penaloza
De La Salle University
Bio
Published December 17, 2019
Keywords
  • crosslinking,
  • encapsulation,
  • chitosan
How to Cite
Agu, A. B. s, Benablo, P. J. L., Mesias, V. S. D., & Penaloza, D. J. P. (2019). SYNTHESIS AND CHARACTERIZATION OF A CHITOSAN-BASED CITRIC ACID-CROSSLINKED ENCAPSULANT SYSTEM. Journal of the Chilean Chemical Society, 64(4), 4610-4612. Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/937

Abstract

An encapsulant system was prepared via crosslinking of chitosan using citric acid as a crosslinker. FTIR spectroscopy, particle size and zeta potential analyses confirmed successful crosslinking, appropriate particle size and colloidal stability. Encapsulation capability of the said material was investigated using fluorescence spectroscopy. The effect of pH on the crosslinked chitosan particles was also conducted.

 

Graph_06.jpg

References

  1. B. Balakrishnan, A. Jayakrishnan, Biomaterials 26, 3941 (2005).
  2. P. Bawa, V. Pillay, Y.E. Choonara, L.C. Du Toit, Biomedical Materials 4, (2009).
  3. M. Dash, F. Chiellini, R.M. Ottenbrite, E. Chiellini, Progress in Polymer Science 36, 981 (2011).
  4. W.R. Gombotz, S.F. Wee, Advanced Drug Delivery Reviews 31, 267 (1998).
  5. E. Khor, L.Y. Lim, Biomaterials 24, 2339, (2003).
  6. G. Kogan, L. Šoltés, R. Stern, P. Gemeiner, Biotechnology Letters 29, 17 (2007).
  7. D.J. McClements, E.A. Decker, Y. Park, J. Weiss, Critical Reviews in Food Science and Nutrition 49, 577 (2009).
  8. W. Paul, C.P. Sharma, S.T.P. Pharma Sciences 10, 5 (2000).
  9. R.A. Sperling, W.J. Parak, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 368, 1333 (2010).
  10. L. Altomare, L. Bonetti, C.E. Campiglio, L. De Nardo, L. Draghi, F. Tana, S. Farè, International Journal of Artificial Organs 41, 337 (2018).
  11. K. Bauri, M. Nandi, P. De, Polymer Chemistry 9, 1257 (2018).
  12. E. Kim, Y. Liu, H. Ben-Yoav, T.E. Winkler, K. Yan, X. Shi, J. Shen, D.L. Kelly, R. Ghodssi, W.E. Bentley, G.F. Payne, Advanced Healthcare Materials 5, 2595 (2016).
  13. T. Kowalczyk, K. Hnatuszko-Konka, A. Gerszberg, A.K. Kononowicz, World Journal of Microbiology and Biotechnology 30, 2141 (2014).
  14. X. Xiao, H. Zhou, K. Qian, Smart Materials and Structures 26 095001 (2017).
  15. C.K.S. Pillai, W. Paul, C.P. Sharma, Progress in Polymer Science 34, 641 (2009).
  16. M. Rinaudo, Progress in Polymer Science 31, 603 (2006).
  17. J. Berger, M. Reist, J.M. Mayer, O. Felt, R. Gurny, European Journal of Pharmaceutics and Biopharmaceutics 57, 35 (2004).
  18. N. Bhattarai, H.R. Ramay, J. Gunn, F.A. Matsen, M. Zhang, Journal of Controlled Release 103, 609 (2005).
  19. C.C. Lin, A.T. Metters, Advanced Drug Delivery Reviews 58, 1379 (2006).
  20. G. Molinaro, J.C. Leroux, J. Damas, A. Adam, Biomaterials 23, 2717 (2002).
  21. M.C.G. Pellá, M.K. Lima-Tenório, E.T. Tenório-Neto, M.R. Guilherme, E.C. Muniz, A.F. Rubira, Carbohydrate Polymers 196, 233 (2018).
  22. H. Tan, C.R. Chu, K.A. Payne, K.G. Marra, Biomaterials 30, 2499 (2009).
  23. M. Wang, Y. Sa, P. Li, Y. Guo, Y. Du, H. Deng, T. Jiang, Y. Wang, Materials Science and Engineering C 90, 264 (2018).
  24. J. Wu, W. Wei, L.Y. Wang, Z.G. Su, G.H. Ma, Biomaterials 28, 2220 (2007).
  25. P. Calvo, C. Remuñán-López, J.L. Vila-Jato, M.J. Alonso, Colloid and Polymer Science 275, 46 (1997).
  26. S. Ogawa, E.A. Decker, D.J. McClements, Journal of Agricultural and Food Chemistry 51, 2806 (2003).
  27. A.J. Ribeiro, C. Silva, D. Ferreira, F. Veiga, European Journal of Pharmaceutical Sciences 25, 31 (2005).
  28. L.Y. Wang, G.H. Ma, Z.G. Su, Journal of Controlled Release 106, 62 (2005).
  29. O. Felt, P. Buri, R. Gurny, Drug Development and Industrial Pharmacy 24, 979 (1998).
  30. M. George, T.E. Abraham, Journal of Controlled Release 114, 1 (2006).
  31. K.A. Janes, M.P. Fresneau, A. Marazuela, A. Fabra, M.J. Alonso, Journal of Controlled Release 73, 255 (2001).
  32. A. Kumari, S.K. Yadav, S.C. Yadav, Colloids and Surfaces B: Biointerfaces 75, 1(2010).
  33. Y. Xu, Y. Du, International Journal of Pharmaceutics 250, 215 (2003).
  34. J. Berger, M. Reist, J.M. Mayer, O. Felt, N.A. Peppas, R. Gurny, European Journal of Pharmaceutics and Biopharmaceutics 57, 19 (2004).
  35. S.C. Chen, Y.C. Wu, F.L. Mi, Y.H. Lin, L.C. Yu, H.W. Sung, Journal of Controlled Release 96, 285 (2004).
  36. M.S. Chiou, H.Y. Li, Journal of Hazardous Materials 93, 233 (2002).
  37. O.A.C. Monteiro, C. Airoldi, International Journal of Biological Macromolecules 26, 119 (1999).
  38. W.S. Wan Ngah, C.S. Endud, R. Mayanar, Reactive and Functional Polymers 50, 181 (2002).
  39. T. Bourtoom, M.S. Chinnan, LWT - Food Science and Technology 41, 1633 (2008).
  40. I. Leceta, P. Guerrero, I. Ibarburu, M.T. Dueñas, K. De La Caba, Journal of Food Engineering 116, 889 (2013).
  41. T. Tanabe, N. Okitsu, A. Tachibana, K. Yamauchi, Biomaterials 23, 817 (2002).
  42. K. Tomihata, Y. Ikada, Biomaterials 18, 567 (1997).
  43. H.B. Fargol, Z. Yue, K.J. Ho, S. Ziqi, M. Victor, A.S. Hamed, H. Yoon‐Uk, I. Masashi, D.S. Xue, Journal of the American Ceramic Society 96, 2636 (2013).
  44. D.P. Penaloza Jr, A. Shundo, K. Matsumoto, M. Ohno, K. Miyaji, M. Goto, K. Tanaka, Soft Matter 9, 5166 (2013).
  45. E.V. Yates, G. Meisl, T.P.J. Knowles, C.M. Dobson, The Journal of Physical Chemistry B 120, 2087 (2016).

Copyright @2019 | Designed by: Open Journal Systems Chile Logo Open Journal Systems Chile Support OJS, training, DOI, Indexing, Hosting OJS

Code under GNU license: OJS PKP