JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 61 No 3 (2016): Journal of the Chilean Chemical Society
Original Research Papers

SYNTHESIS OF 1-ARYL-6,6-DIMETHYL-2-PHENYL-6,7-DIHYDRO-1H-INDOL-4(5H)-ONES BY TWO STEPS, IN A THREE-COMPONENT REACTION

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  • Jabbar Khalafy,
  • Fahimeh Badparvar,
  • Ahmad Poursattar Marjani
Jabbar Khalafy
Department of Chemistry, Faculty of Science, Urmia University
Fahimeh Badparvar
Department of Chemistry, Faculty of Science, Urmia University
Ahmad Poursattar Marjani
Department of Chemistry, Faculty of Science, Urmia University
Published September 10, 2016
Keywords
  • Phenacyl bromide,
  • Dimedone,
  • Anilines,
  • 1H-Indol-4(5H)-ones,
  • Three-component reaction
How to Cite
Khalafy, J., Badparvar, F., & Marjani, A. P. (2016). SYNTHESIS OF 1-ARYL-6,6-DIMETHYL-2-PHENYL-6,7-DIHYDRO-1H-INDOL-4(5H)-ONES BY TWO STEPS, IN A THREE-COMPONENT REACTION. Journal of the Chilean Chemical Society, 61(3). Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/89

Copyright (c) 2017 Jabbar Khalafy, Fahimeh Badparvar, Ahmad Poursattar Marjani

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Abstract

An efficient method for the synthesis of 1-aryl-6,6-dimethyl-2-phenyl-6,7-dihydro-1H-indol-4(5H)-ones is achieved in two steps, using a three-component reaction of phenacyl bromide, dimedone and aniline derivatives in water-ethanol (1:1) under reflux conditions. 

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