JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 61 No 3 (2016): Journal of the Chilean Chemical Society
Original Research Papers

PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA

Sebastián Castro-Saavedra
School of Forestry Engineering, Universidad Mayor Department of Chemistry, Faculty of Sciences, University of Chile
Gonzalo Fuentes-Barros
School of Forestry Engineering, Universidad Mayor Department of Chemistry, Faculty of Sciences, University of Chile
Cristian Tirapegui
Department of Chemistry, Faculty of Sciences, University of Chile
Williams Acevedo-Fuentes
Department of Chemistry, Faculty of Sciences, University of Chile
Bruce K. Cassels
Department of Chemistry, Faculty of Sciences, University of Chile
Andrés Barriga
CEPEDEQ, Faculty of Chemical and Pharmaceutical Sciences, University of Chile
Marcelo Vilches-Herrera
Department of Chemistry, Faculty of Sciences, University of Chile
Published September 10, 2016
How to Cite
Castro-Saavedra, S., Fuentes-Barros, G., Tirapegui, C., Acevedo-Fuentes, W., Cassels, B. K., Barriga, A., & Vilches-Herrera, M. (2016). PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA. Journal of the Chilean Chemical Society, 61(3). Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/82

Abstract

A phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous characterization of four known alkaloids by NMR techniques: boldine, laurolitsine, laurotetanine and norglaucine, in addition to the previously identified reticuline, and the identification via UHPLC-MS of seven more alkaloids, coclaurine, N-methylcoclaurine, norreticuline, isocorydine, N-methyllaurotetanine, predicentrine and glaucine. In spite of this fairly broad variety of benzyltetrahydroisoquinolines and aporphines, the concentrations of these alkaloids in the different organs of C. alba are quite low, which is in contrast with the sometimes generous yields of alkaloids in this genus.

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