Vol 61 No 3 (2016): Journal of the Chilean Chemical Society
Original Research Papers
LACASSE CATALYZED-SYNTHESIS OF 4,4’-BIPHENYLDIAMINE FROM P-CHLOROANILINE. EVALUATION OF ANTIFUNGAL AND ANTIOXIDANT ACTIVITIES
Published
May 23, 2017
Keywords
- P-chloroaniline,
- 4,
- 4’-Biphenyldiamine,
- Laccase,
- Antioxidant activity
- Antifungal activity ...More
How to Cite
Campos, A. M., Mendoza, L., Vásquez, J., Melo, R., Salas, J., & Cotoras, M. (2017). LACASSE CATALYZED-SYNTHESIS OF 4,4’-BIPHENYLDIAMINE FROM P-CHLOROANILINE. EVALUATION OF ANTIFUNGAL AND ANTIOXIDANT ACTIVITIES. Journal of the Chilean Chemical Society, 61(3). Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/67
Copyright (c) 2017 Ana M. Campos, Leonora Mendoza, Juan Vásquez, Ricardo Melo, Jennifer Salas, Milena Cotoras
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Abstract
Laccase is a copper-containing oxidase that catalyzes reduction of molecular oxygen to water and the oxidation of a phenolic compound. In this paper, laccase was utilized to synthesize 4,4’-Biphenyldiamine using p-chloroaniline as substrate by means of a coupling reaction. The synthesized compound, 4,4’-Biphenyldiamine, presented low antifungal activity against the phytopathogenic fungus Botrytis cinerea, however the antioxidant ability, measurement by ORAC-PGR method, was higher than substrate.
This work corresponds to the first report of synthesis 4,4’-Biphenyldiamine, from p-chloroaniline in a lacasse-catalyzed reaction.
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