JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 62 No 3 (2017): Journal of the Chilean Chemical Society
Original Research Papers

SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES

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  • Sadia Naureen,
  • Fatima Ijaz,
  • Munawar Ali Munawar,
  • Nadia Asif,
  • Faryal Chaudhry,
  • Muhammad Ashraf,
  • Misbahul Ain Khan
Sadia Naureen
Institute of Chemistry, University of the Punjab, Quaid-e-Azam campus
Fatima Ijaz
Institute of Chemistry, University of the Punjab, Quaid-e-Azam campus
Munawar Ali Munawar
Institute of Chemistry, University of the Punjab, Quaid-e-Azam campus
Nadia Asif
Institute of Chemistry, University of the Punjab, Quaid-e-Azam campus
Faryal Chaudhry
Institute of Chemistry, University of the Punjab, Quaid-e-Azam campus
Muhammad Ashraf
Department of Chemistry, The Islamia University of Bahawalpur Department of Biochemistry and Biotechnology, The Islamia University of Bahawalpur
Misbahul Ain Khan
Institute of Chemistry, University of the Punjab, Quaid-e-Azam campus Department of Chemistry, The Islamia University of Bahawalpur
Published September 2, 2017
Keywords
  • Imidazole,
  • Indole,
  • antitumor,
  • ammonium acetate
How to Cite
Naureen, S., Ijaz, F., Ali Munawar, M., Asif, N., Chaudhry, F., Ashraf, M., & Ain Khan, M. (2017). SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES. Journal of the Chilean Chemical Society, 62(3). Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/315

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Abstract

Indole-based tetraarylimidazoles were prepared by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines and ammonium acetate in acetic acid. The new compounds were evaluated for their antiurease and antioxidant activity. The synthesized compounds exhibited potent antiurease activity.

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