Vol 66 No 2 (2021): Journal of the Chilean Chemical Society
Original Research Papers
SYNTHESIS OF 6-TERT-OCTYL AND 6,8-DITERT-BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
Published
June 13, 2021
Keywords
- COUMARINS,
- hydrophobic,
- TRPV1
How to Cite
Zárraga Olavarría, M., Dahrouch, M., Lisboa, E., Arroyo, P., & Miranda, A. (2021). SYNTHESIS OF 6-TERT-OCTYL AND 6,8-DITERT-BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST. Journal of the Chilean Chemical Society, 66(2), 5220-5222. Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/1740
Copyright (c) 2021 SChQ
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Abstract
In this study, the synthesis of new coumarins with aliphatic chains is discussed. The incorporation of the 6-tert-octyl and 6,8-ditert-butyl chains into a coumarin structure from alkylphenols, allows obtaining hydrophobic coumarins with good yields. These coumarins can be potential modulators of TRPV1 receptors. Synthesis and spectroscopic data of these new coumarins are analyzed.
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