JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 66 No 1 (2021): Journal of the Chilean Chemical Society
Original Research Papers

PHYTOCHEMICAL STUDY OF ENDEMIC COSTA RICAN ANNONACEAE SPECIES ANNONA PITTIERI AND CYMBOPETALUM COSTARICENSE

Jonathan Parra
University of Costa Rica
Published February 9, 2021
Keywords
  • Annonaceae,
  • Annona pittieri,
  • Cymbopetalum costaricense,
  • squamocin
How to Cite
Parra, J. (2021). PHYTOCHEMICAL STUDY OF ENDEMIC COSTA RICAN ANNONACEAE SPECIES ANNONA PITTIERI AND CYMBOPETALUM COSTARICENSE. Journal of the Chilean Chemical Society, 66(1), 5047-5050. Retrieved from https://jcchems.com/index.php/JCCHEMS/article/view/1530

Abstract

 

1530.jpgThe Central American rain forest endemic Annonaceae species, Annona pittieri and Cymbonopetallum costaricense, were studied looking for molecules with bioactive potential. The acetogenin Squamocin (1) isolated from A. pittieri showed cytotoxic activity against human acute lymphocytic leukaemia with a good selectivity against healthy blood cells. Additionally, from A. pittieri nine molecules were isolated, including a new 2-azaanthraquinone alkaloid, 4-methoxybenzo[g]isoquinoline-5,10-dione (2). From C. costaricense three molecules were isolated including a new 1-azaanthraquinone alkaloid, 6-hydroxy-9-methoxy-cleistopholine (3).

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